Indications - Doxepin cream is indicated for the short-term (upto 8 days) management of moderate pruritus in adult patients with atopic dermatitis or lichen simplex chronicus.

Dosage & Administration - Adult and child over 12 years: apply thinly 3–4 times daily; usual max. 3 g per application; usual total max. 12 g daily; coverage should be less than 10% of body surface area.

Side Effects - Drowsiness, local burning, stinging, irritation, tingling, rash; systemic side-effects such as antimuscarinic effects, headache, fever, dizziness, gastro-intestinal disturbances has been reported.

Contraindications - Patients with untreated narrow angle glaucoma or a tendency to urinary retention because doxepin has an anticholinergic effect Individuals who have shown previous sensitivity to any of its components

Others - Pregnancy & Lactation Pregnancy: Category B- There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Nursing Mothers: Doxepin is excreted in human milk after oral administration. It is possible that doxepin may also be excreted in human milk following topical application of Doxepin cream.